13/12/2017
ALBA Synchrotron Works for People’s Health
ALBA Synchrotron Works for People’s Health
Two recent works remind us that ALBA synchrotron is a very valuable tool to help develop new drugs.
On one hand, using the MIRAS beam line of the ALBA synchrotron (infrared radiations), researchers from the Universitat Autònoma de Barcelona (UAB) and the ALBA Synchrotron have demonstrated in a paper the capability of metalosomes - aggregates made of phospholipids and metal complexes - to interact with cells and release carbon monoxide in a controlled way (CO release can be beneficial because of its anti-inflammatory, vasodilator and cardio protective properties).
On the other hand, in another publication, a team led by researchers from the Universitat Politècnica de Catalunya (UPC) has unveiled the mechanism of action of two drugs, FR60 and JNI18, which cure 100% of mice with sleeping sickness. Using X-rays of the ALBA XALOC beam line, they have observed how these drugs perfectly stacked on the Trypanosoma brucei’s DNA, the parasite that causes the disease (image). Blocking and inflicting specific damage on its DNA, the parasite cannot reproduce and finally dies after 4-5 days.
On one hand, using the MIRAS beam line of the ALBA synchrotron (infrared radiations), researchers from the Universitat Autònoma de Barcelona (UAB) and the ALBA Synchrotron have demonstrated in a paper the capability of metalosomes - aggregates made of phospholipids and metal complexes - to interact with cells and release carbon monoxide in a controlled way (CO release can be beneficial because of its anti-inflammatory, vasodilator and cardio protective properties).
On the other hand, in another publication, a team led by researchers from the Universitat Politècnica de Catalunya (UPC) has unveiled the mechanism of action of two drugs, FR60 and JNI18, which cure 100% of mice with sleeping sickness. Using X-rays of the ALBA XALOC beam line, they have observed how these drugs perfectly stacked on the Trypanosoma brucei’s DNA, the parasite that causes the disease (image). Blocking and inflicting specific damage on its DNA, the parasite cannot reproduce and finally dies after 4-5 days.
More news
06/09/2017
Thanks to MARES, SENER takes care of the physical well-being of the astronauts
30/08/2017
The Nanoworld Is Designed and Observed In and Nearby Barcelona Synchrotron Park
26/07/2017
The UAB Research Park: from the infinitely small to the infinitely big
19/07/2017
Barcelona Synchrotron Park’s key value: the environment
13/07/2017
SENER, 50 Years In Space!
04/07/2017
Barcelona Synchrotron Park Sponsors the Sixth Ideas Generation Program
home